A375 Xenografts

 

 

Rincon Bio performs A375 xenograft models to test efficacy of preclinical therapies.  Please see below for additional information or to request a quote. 

Melanoma

Organism: Homo sapiens, human  /  Tissue: skin  /  Disease: malignant melanoma

Notes

A375 were derived from a 54 year old female with malignant melanoma

in vivo

Used as a syngeneic model.  Implanted tumor cells create a model in which to test the efficacy of novel immunotherapies 

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Receive a quote within one business day for a A375 Xenograft

Rincon Bio Growth Curve

A375 Vemurafenib Positive Control

A375.png

Cell Line: A375

Mouse Strain: Athymic Nude from Envigo

Gender: Female

Positive Control: Vemurafenib

Concentration: 15mg/kg

Matrigel: Yes

Cells Implanted per Animal: 5 million

Implanted: 2/14/19

Stratified: 3/8/19

From implant to stratification: 22 days

Stratification Size: 170mm^3

Dosing: Vehicle - Tail Vein IV dosed once a week for 3 weeks, Vemurafenib - Oral dosing daily for 20 days

WHY WORK WITH

RINCON BIO?

DOMESTIC QUALITY at COMPETITIVE PRICES

 

When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices

SPEED TO INITIATION
 

Most efficacy studies can be initiated within two business days.

PERSONAL TOUCH

 

We love our clients!  We are flexible and easy to work with.  And we take a personal interest in our clients' studies.