Rincon Bio performs A375 xenograft models to test efficacy of preclinical therapies. Please see below for additional information or to request a quote.
Organism: Homo sapiens, human / Tissue: skin / Disease: malignant melanoma
A375 were derived from a 54 year old female with malignant melanoma
Used as a syngeneic model. Implanted tumor cells create a model in which to test the efficacy of novel immunotherapies
Rincon Bio Growth Curve
A375 Vemurafenib Positive Control
Cell Line: A375
Mouse Strain: Athymic Nude from Envigo
Positive Control: Vemurafenib
Cells Implanted per Animal: 5 million
From implant to stratification: 22 days
Stratification Size: 170mm^3
Dosing: Vehicle - Tail Vein IV dosed once a week for 3 weeks, Vemurafenib - Oral dosing daily for 20 days
WHY WORK WITH
When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices
Most efficacy studies can be initiated within two business days.
We love our clients! We are flexible and easy to work with. And we take a personal interest in our clients' studies.