A375 Xenografts
Rincon Bio performs A375 xenograft models to test efficacy of preclinical therapies. Please see below for additional information or to request a quote.
Melanoma
Organism: Homo sapiens, human / Tissue: skin / Disease: malignant melanoma
Notes
A375 were derived from a 54 year old female with malignant melanoma
in vivo
Used as a syngeneic model. Implanted tumor cells create a model in which to test the efficacy of novel immunotherapies
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Rincon Bio Growth Curve
A375 Vemurafenib Positive Control
Cell Line: A375
Mouse Strain: Athymic Nude from Envigo
Gender: Female
Positive Control: Vemurafenib
Concentration: 15mg/kg
Matrigel: Yes
Cells Implanted per Animal: 5 million
Implanted: 2/14/19
Stratified: 3/8/19
From implant to stratification: 22 days
Stratification Size: 170mm^3
Dosing: Vehicle - Tail Vein IV dosed once a week for 3 weeks, Vemurafenib - Oral dosing daily for 20 days
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RINCON BIO?
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When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices
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