COLO-205 Xenografts
Rincon Bio performs COLO-205 xenograft models to test efficacy of preclinical therapies. Please see below for additional information or to request a quote.
Colon
COLO-205 cells were derived from a 70 year old Caucasian male with carcinoma of the colon
Oncogene
Carcinoembryonic antigen (CEA) 1.5 to 4.1 ng/10 exp6 cells/10 days; keratin; interleukin 10 (IL-10, interleukin-10),The cells are positive for keratin by immunoperoxidase staining.
The cells are CSAp negative (CSAp-).
The cells are positive for keratin by immunoperoxidase staining.
COLO 205 cells express a 36000 dalton cell surface glycoprotein related to the GA733-2 tumor associated antigen. Ref
in vivo
Used in xenografts to test the efficacy of novel cancer therapeutics
Cells grow in nude mice (Tumors develop within 21 days in nude mice inoculated subcutaneously with 10(7) cells). Ref
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Rincon Bio Growth Curve
Colo-205
Cell Line: Colo-205
Mouse Strain: Athymic Nude Envigo
Animals per Group: 10
Positive Control: None
Concentration: N/A
Matrigel: Yes
Dosing: N/A
From implant to stratification: 7
Cells Implanted per Animal: 10 million
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