DoHH2

Leukemia/

Lymphoma

DoHH2 was derived from a 60 year old man with non-Hodgkin's lymphoma

Notes

DoHH2 is an EBV-negative cell line.  The cells express IgG lambda, are reactive with CD10 and CD19 monoclonal antibodies, and show by cytogenetic analysis 48,XY, +7, +del(12)(q24), t(14;18)(q32;q21)

in vivo

Used in allogeneic xenografts

Tumors grow in athymic BALB/C or NOD/SCID

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