SW480 Xenograft

 

 

Rincon Bio performs SW480 xenograft models to test efficacy of preclinical therapies.  Please see below for additional information or to request a quote. 

Colon

SW480 were derived from a 50 year old Caucasian male with colorectal adenocarcinoma

Oncogene

myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -

carcinoembryonic antigen (CEA) 0.7 ng/10 6 cells/10 days; keratin; transforming growth factor beta,myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -,HLA A2, B8, B17; blood type A; Rh+,The cells are positive for keratin by immunoperoxidase staining.,The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes. Ref

in vivo

Used in xenografts to test the efficacy of novel cancer therapeutics 

Tumors develop within 21 days in nude mice inoculated subcutaneously with 10(7) cells

Request Quote

Receive a quote within one business day for a SW480 Xengraft

Rincon Bio Growth Curve

sw480.png

Cell Line: SW480 

Mouse Strain: Hsd:Athymic Nude-Foxn1nu (Envigo female) 

Animals per Group: 10 

Positive Control: None 

Concentration: N/A 

Matrigel: Yes 

Dosing: N/A 

From implant to stratification: 21 days 

Cells Implanted per Animal: 10 million

WHY WORK WITH

RINCON BIO?

DOMESTIC QUALITY at COMPETITIVE PRICES

 

When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices

SPEED TO INITIATION
 

Most efficacy studies can be initiated within two business days.

PERSONAL TOUCH

 

We love our clients!  We are easy to work with.  And we take a personal interest in our clients and their studies.