Rincon Bio performs SW480 xenograft models to test efficacy of preclinical therapies. Please see below for additional information or to request a quote.
SW480 were derived from a 50 year old Caucasian male with colorectal adenocarcinoma
myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -
carcinoembryonic antigen (CEA) 0.7 ng/10 6 cells/10 days; keratin; transforming growth factor beta,myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -,HLA A2, B8, B17; blood type A; Rh+,The cells are positive for keratin by immunoperoxidase staining.,The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes. Ref
Used in xenografts to test the efficacy of novel cancer therapeutics
Tumors develop within 21 days in nude mice inoculated subcutaneously with 10(7) cells
Rincon Bio Growth Curve
Cell Line: SW480
Mouse Strain: Hsd:Athymic Nude-Foxn1nu (Envigo female)
Animals per Group: 10
Positive Control: None
From implant to stratification: 21 days
Cells Implanted per Animal: 10 million
WHY WORK WITH
When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices
Most efficacy studies can be initiated within two business days.
We love our clients! We are easy to work with. And we take a personal interest in our clients and their studies.