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WiDr

Colon

WiDr cells were derived from a 78 year old female with colon cancer 

Oncogene

carcinoembryonic antigen (CEA) 118 ng/10 exp6 cells/10 days; Colon Specific Antigen (CSAp); transforming growth factor beta; keratin,HLA A24, A32, B15, B18. The cells are positive for keratin by immunoperoxidase staining. The cells expressed p53 antigen (the p53 produced has a G -> A mutation resulting in Arg -> His at position 273). Ref

in vivo

Used in allogeneic xenografts

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Tumors develop within 21 days in nude mice inoculated subcutaneously with 10(7) cells

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