top of page
PL-21
Leukemia/
Lymphoma
PL-21 was derived from a 24 year old man with refractory acute promyelocytic leukemia after granulocytic sarcoma
Notes
PL-21 cells do not carry the t(15;17); based on morphology, surface marker expression of CD14/CD68 and expression of the monocyte-specific esterase, PL-21 cells appear to be rather of monocytic origin; differentiation is inducible by phorpbol ester; cells carry an FLT3 internal tandem duplication. Ref
in vivo
Used in allogeneic xenografts
Tumors grow in nude mice
Request Quote
Receive a quote within one business day
bottom of page