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CANCER EFFICACY 

MODELS

QUOTE REQUEST FORM

xenograft or syngeneic studies

Rincon Bio performs allogeneic and syngeneic xenograft studies. 
 
Xenograft models entail the implantation of human cancer cells into a host animal, typically an immunocompromised mouse or rat.  Xenograft tumor models are effective tools for assessing in vivo efficacy of candidate cancer drugs.   
​
With syngeneic models, the tumor cell line is derived from the same species as the host animal.  Syngeneic models can thus test the efficacy of immuno-oncology agents as single therapies, or in combination with other anti-cancer drugs.  Rincon Bio performs syngeneic studies in mice.
​
Other options include custom xenograft study designs, fluorescent imaging, MTD studies, pre-clinical drug formulation, tumor collection, organ collection, histology, and pharmacodynamic studies (ELISA, Luminex, PCR, sequencing). 

Please see below for available models

Please fill out the form below

We will respond with a quote within one business day

Route of Administration?
Other options:
Is the planned study part of a grant application?

AVAILABLE MODELS

Filter items with Model Type
Filter items with Organ
Cell line
Model Type
Organ
Mutations
Weeks from stratification to termination (average)
22Rv1
Xenograft
Prostate
KMT2D, PIK3CA, TP53
5
4T1
Syngeneic
Breast
Unavailable
4
786-0
Xenograft
Renal
PTEN, TERT, TP53, VHL
N/A
A-375
Xenograft
Skin
BRAF, CDKN2A, TERT
4
A20
Syngeneic
Blood
Unavailable
N/A
A431
Xenograft
Skin
TP53, EGFR-PPARGC1A fussion
N/A
A498
Xenograft
Renal
PIK3CB, VHL
5
A549
Xenograft
Lung
KRAS, STK11, TP53
6
A673
Xenograft
Sarcoma
BRAF, TP53, EWS-FLI1 fusion
3
AB22
Syngeneic
Lung
CDKN2A
N/A
AGS
Xenograft
Gastric
CTNNB1, KRAS, PIK3CA, TP53
6
B16-F10
Syngeneic
Skin
Unavailable
2
BxPc-3
Xenograft
Pancreatic
BRAF, KRAS, TP53
7
CHLA-06
Xenograft
Brain
TP53
6
CT26
Syngeneic
Colon
KRAS
2.5
CT26.CL25
Syngeneic
Colon
KRAS
2.5
Caki-1
Xenograft
Renal
RB1
4
Cloudman S91
Syngeneic
Skin
Unavailable
N/A
Colo-205
Xenograft
Colon
APC, BRAF, CTNNB1, TP53
2.5
Colon-26 (MC26)
Syngeneic
Colon
Unavailable
4
D4M3A
Syngeneic
Skin
Unavailable
2
DLD-1
Xenograft
Colon
APC, ACVR2A, B2M, EP300, KRAS, PIK3CA, TGFBR2, TP53
4
DU-145
Xenograft
Prostate
CDKN2A, RB1, STK11, TP53
6
EMT6
Syngeneic
Breast
Unavailable
5
ES-2-luc
Xenograft
Ovarian
BRAF, PALB2, TERT, TP53
3.5
HCC1954
Xenograft
Breast
PIK3CA, TP53, CLTC-VMP1 fusion
7
HCT-116
Xenograft
Colon
ACVR2A, BRCA2, CDKN2A, CTNNB1, EP300, KRAS, PIK3CA, PPM1D, TGFBR2, TP53
5
HT-29
Xenograft
Colon
APC, BRAF, PIK3CA, SMAD4, TP53
N/A
HuCCT1
Xenograft
Bile Duct
KRAS, MSH6, TP53
5
Huh-7
Xenograft
Liver
KDR, POLD3, TERT, TP53
4
JIMT-1
Xenograft
Breast
PIK3CA, TP53
8
JeKo-1
Xenograft
Blood
TP53
5
LASCPC-01
Xenograft
Prostate
Unavailable
3
LNCaP
Xenograft
Prostate
AR, MEN1, PIK3R1, PTEN, TP53
4
Lewis Lung LLC1
Syngeneic
Lung
Unavailable
3
MBT-2
Syngeneic
Bladder
Unavailable
5.5
MC38
Syngeneic
Colon
Unavailable
4
MDA-MB-231
Xenograft
Breast
CDKN2A, CDKN2B, BRAF, KRAS, TERT, TP53
4
MDA-MB-468
Xenograft
Breast
PTEN, RB1, TP53
N/A
MIAPaCa-2
Xenograft
Pancreatic
KRAS, TP53
8
MOLM-13
Xenograft
Blood
FLT3, KMT2A-MLLT3 fusion
14
NCI-H1703
Xenograft
Lung
CDKN2A, TP53
3
NCI-H1975
Xenograft
Lung
EGFR, PIK3CA, TP53
6
NCI-H460
Xenograft
Lung
KRAS, PIK3CA, STK11, TP53
5
NCI-N87
Xenograft
Gastric
ERBB3, TP53
6
OCI-AML-3
Xenograft
Blood
DNMT3A, NRAS, NPM1
2
OCI-Ly1
Xenograft
Blood
Unavailable
N/A
OVCAR8
Xenograft
Ovarian
CTNNB1, ERBB2, KRAS, TP53
8
P388
Syngeneic
Blood
Unavailable
N/A
PANC-1
Xenograft
Pancreatic
KRAS, TP53
3
PC-3
Xenograft
Prostate
TP53
4
SK-BR-3
Xenograft
Breast
TP53
4
SK-N-FI
Xenograft
Brain
NF1, TP53
4
SK-N-MC
Xenograft
Sarcoma
TP53, EWS-FLI1 fusion
3
SK-OV-3
Xenograft
Ovarian
APC, FBXW7, PIK3CA, TP53
10
SKM-1
Xenograft
Blood
ASXL1, BCORL1, EZH2, KRAS, TP53
3
SU-DHL-16
Xenograft
Blood
Unavailable
4
SW480
Xenograft
Colon
APC, KRAS, TP53
4
TT
Xenograft
Thyroid
RET, TBX3
4
U-87MG
Xenograft
Brain
Unavailable
3
U118-MG
Xenograft
Brain
IDH1, PTEN, TP53
6
UM-UC-3
Xenograft
Bladder
KRAS, PARD3B, TERT, TP53
N/A
VcAP
Xenograft
Prostate
MLH1, TP53, TMPRss2-ERG fusion
N/A
WITT (SK-Cha-1)
Xenograft
Bile Duct
Unavailable
N/A
WM164
Xenograft
Skin
BRAF
6
YAPC
Xenograft
Pancreatic
KRAS, TP53
N/A

*Other Models are possible, please contact us for details

WHY WORK WITH

RINCON BIO?

DOMESTIC QUALITY at COMPETITIVE PRICES

 

When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices

SPEED TO INITIATION
 

Most efficacy studies can be initiated within two business days.

PERSONAL TOUCH

 

We love our clients!  We are easy to work with.  And we take a personal interest in our clients and their studies.  

VIVARIUMS

Our vivariums are equipped with mouse towers, biosafety cabinets, and an IVIS imaging system.

Email: info@rinconbio.com
Tel:  760-713-6613

​

Utah: 

3900 N Traverse Mountain Blvd

Suite 100

Lehi, UT 84043

​

California: 

3156 Vista Way, Suite 220

Oceanside, CA 92056

 

CONTACT US
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