SYNGENEIC
MOUSE
MODELS
DOMESTIC QUALITY at COMPETITIVE PRICES
When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices
In a syngeneic mouse model, the tumor cell line is derived from the same species as the host animal. Syngeneic models can thus test the efficacy of immuno-oncology agents as single therapies, or in combination with other anti-cancer drugs. Please see list of available models below.
Other options include:
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Custom study designs
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Fluorescent imaging
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MTD studies
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Pre-clinical drug formulation
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Tumor collection, organ collection, histology
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Pharmacodynamic studies (e.g. ELISA, Luminex, PCR, sequencing, flow cytometry)
Please see below for our available models or to request a quote
SYNGENEIC
cell lines
Cell line | Organ | Weeks from stratification to termination (average) | Growth Curve |
---|---|---|---|
4T1 | Breast | 4 | |
A20 | Blood | N/A | |
AB22 | Lung | N/A | |
B16-F10 | Skin | 2 | |
CT26 | Colon | 2.5 | |
CT26.CL25 | Colon | 2.5 | |
Cloudman S91 | Skin | N/A | |
Colon-26 (MC26) | Colon | 4 | |
D4M3A | Skin | 2 | |
EMT6 | Breast | 5 | |
Lewis Lung LLC1 | Lung | 3 | |
MBT-2 | Bladder | 5.5 | |
MC38 | Colon | 4 | |
P388 | Blood | N/A |
*Other cell lines are possible, please contact us about your cell line of choice
MEET OUR SCIENTIFIC DIRECTOR
Bret Stephens, PhD
Dr. Stephens has a broad in vivo biology background that comes from twenty years of involvement in cancer drug discovery in both academic and pharmaceutical industry settings.
Dr. Stephens received his PhD in Molecular Biology from the University of Arizona.
Previous to joining Rincon Bio, Dr. Stephens worked at Tolero Pharmaceuticals, Huntsman Cancer Institute (University of Utah), and the BioDesign Institute (Arizona State University), where he focused on cancer small molecule drug development.
ABOUT US
Founded in 2013, Rincon Bio is a pre-clinical CRO focusing on in vivo cancer efficacy studies, both allogeneic (human cell models) and syngeneic (immunotherapy models).
The staff at Rincon Bio have performed hundreds of efficacy studies for pharmaceutical researchers across the United States and Europe, both in industry and in academia. We've worked in the world of small, agile, start-up pharma, which gives us a unique perspective as a CRO. We appreciate that your priorities change quickly, and you need a partner that can adapt along with you. Furthermore, we can initiate most efficacy studies more quickly than any other CRO.
We understand the importance of transparency and communication: at Rincon Bio, our clients are assigned a single point-of-contact, who is responsible for managing their study from conception to completion.
Rincon Bio is a US-based organization, born from a desire to simplify the process of running cancer efficacy studies, and to provide domestic quality at competitive prices. We are The Cancer Model CRO - we believe in doing one thing, and doing it well.
If you do decide to run your study at Rincon Bio, the process will be easy, streamlined, and pleasant.
Email: info@rinconbio.com
Tel: 760-713-6613
Utah:
3900 N Traverse Mountain Blvd
Suite 100
Lehi, UT 84043
California:
3156 Vista Way, Suite 220
Oceanside, CA 92056