A20 - Syngeneic Model
Rincon Bio performs A20 syngeneic models to test efficacy of immunotherapies. Please see below for additional information or to request a quote.
Lymphoma
The A20 cell line is a BALB/c B cell lymphoma line derived from a spontaneous reticulum cell neoplasm found in an old BALB/cAnN mouse. Ref
Notes
The cells express little surface immunoglobulin when grown in Click's medium; however, they express large amounts when grown in RPMI 1640 medium. The cells can present both alloantigens and protein antigens. Ref
in vivo
Used as a syngeneic model. Implanted tumor cells create a model in which to test the efficacy of novel immunotherapies
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Rincon Bio Growth Curves
A20 Growth with Matrigel
Internal Curve
Cell Line: A20
Mouse Strain: Balb/C
No Positive Control
Matrigel was used
No dosing
Implanted 3/20/19
No stratifiaction
Cells implanted: 1 million
A20 Growth without Matrigel
Internal Curve
Cell Line: A20
Mouse Strain: Balb/C
No Positive Control
Matrigel was not used
No dosing
Implanted 2/12/19
No stratifiaction
Cells implanted: 790k
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