A20 - Syngeneic Model

 

Rincon Bio performs A20 syngeneic models to test efficacy of immunotherapies.  Please see below for additional information or to request a quote. 

Lymphoma

The A20 cell line is a BALB/c B cell lymphoma line derived from a spontaneous reticulum cell neoplasm found in an old BALB/cAnN mouse. Ref

Notes

The cells express little surface immunoglobulin when grown in Click's medium; however, they express large amounts when grown in RPMI 1640 medium. The cells can present both alloantigens and protein antigens. Ref

in vivo

Used as a syngeneic model.  Implanted tumor cells create a model in which to test the efficacy of novel immunotherapies 

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Rincon Bio Growth Curves

A20 Growth with Matrigel

a20.png

Internal Curve

Cell Line: A20

Mouse Strain: Balb/C

No Positive Control

Matrigel was used

No dosing

Implanted 3/20/19

No stratifiaction

Cells implanted: 1 million

A20 Growth without Matrigel

a20 nmg.png

Internal Curve

Cell Line: A20

Mouse Strain: Balb/C

No Positive Control

Matrigel was not used

No dosing

Implanted 2/12/19

No stratifiaction

Cells implanted: 790k

WHY WORK WITH

RINCON BIO?

DOMESTIC QUALITY at COMPETITIVE PRICES

 

When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices

SPEED TO INITIATION
 

Most efficacy studies can be initiated within two business days.

PERSONAL TOUCH

 

We love our clients.  We are easy to work with.  And we develop a personal interest in our clients and their studies.