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CANCER EFFICACY 

MODELS

QUOTE REQUEST FORM

xenograft or syngeneic studies

Rincon Bio performs allogeneic and syngeneic xenograft studies. 
 
Xenograft models entail the implantation of human cancer cells into a host animal, typically an immunocompromised mouse or rat.  Xenograft tumor models are effective tools for assessing in vivo efficacy of candidate cancer drugs.   

With syngeneic models, the tumor cell line is derived from the same species as the host animal.  Syngeneic models can thus test the efficacy of immuno-oncology agents as single therapies, or in combination with other anti-cancer drugs.  Rincon Bio performs syngeneic studies in mice.

Other options include custom xenograft study designs, fluorescent imaging, MTD studies, pre-clinical drug formulation, tumor collection, organ collection, histology, and pharmacodynamic studies (ELISA, Luminex, PCR, sequencing). 

Please see below for available models

Please fill out the form below

We will respond with a quote within one business day

Route of Administration?
Other options:
Is the planned study part of a grant application?

AVAILABLE MODELS

Filter items with Model Type
Filter items with Organ
Cell line
Model Type
Organ
Mutations
Weeks from stratification to termination (average)
ES-2-luc
Xenograft
Ovarian
BRAF, PALB2, TERT, TP53
3.5
HCC1954
Xenograft
Breast
PIK3CA, TP53, CLTC-VMP1 fusion
7
HCT-116
Xenograft
Colon
ACVR2A, BRCA2, CDKN2A, CTNNB1, EP300, KRAS, PIK3CA, PPM1D, TGFBR2, TP53
5
HT-29
Xenograft
Colon
APC, BRAF, PIK3CA, SMAD4, TP53
N/A
HuCCT1
Xenograft
Bile Duct
KRAS, MSH6, TP53
5
Huh-7
Xenograft
Liver
KDR, POLD3, TERT, TP53
4
JIMT-1
Xenograft
Breast
PIK3CA, TP53
8
JeKo-1
Xenograft
Blood
TP53
5
LASCPC-01
Xenograft
Prostate
Unavailable
3
LNCaP
Xenograft
Prostate
AR, MEN1, PIK3R1, PTEN, TP53
4
Lewis Lung LLC1
Syngeneic
Lung
Unavailable
3
MBT-2
Syngeneic
Bladder
Unavailable
5.5

*Other Models are possible, please contact us for details

WHY WORK WITH

RINCON BIO?

DOMESTIC QUALITY at COMPETITIVE PRICES

 

When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices

SPEED TO INITIATION
 

Most efficacy studies can be initiated within two business days.

PERSONAL TOUCH

 

We love our clients!  We are easy to work with.  And we take a personal interest in our clients and their studies.  

VIVARIUMS

Our vivariums are equipped with mouse towers, biosafety cabinets, and an IVIS imaging system.

Email: info@rinconbio.com
Tel:  760-713-6613

Utah: 

3900 N Traverse Mountain Blvd

Suite 100

Lehi, UT 84043

California: 

3156 Vista Way, Suite 220

Oceanside, CA 92056

 

CONTACT US
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