top of page

CANCER EFFICACY 

MODELS

QUOTE REQUEST FORM

xenograft or syngeneic studies

Rincon Bio performs allogeneic and syngeneic xenograft studies. 
 
Xenograft models entail the implantation of human cancer cells into a host animal, typically an immunocompromised mouse or rat.  Xenograft tumor models are effective tools for assessing in vivo efficacy of candidate cancer drugs.   

With syngeneic models, the tumor cell line is derived from the same species as the host animal.  Syngeneic models can thus test the efficacy of immuno-oncology agents as single therapies, or in combination with other anti-cancer drugs.  Rincon Bio performs syngeneic studies in mice.

Other options include custom xenograft study designs, fluorescent imaging, MTD studies, pre-clinical drug formulation, tumor collection, organ collection, histology, and pharmacodynamic studies (ELISA, Luminex, PCR, sequencing). 

Please see below for available models

Please fill out the form below

We will respond with a quote within one business day

Route of Administration?
Other options:
Is the planned study part of a grant application?

AVAILABLE MODELS

Filter items with Model Type
Filter items with Organ
Cell line
Model Type
Organ
Mutations
Weeks from stratification to termination (average)
MC38
Syngeneic
Colon
Unavailable
4
MDA-MB-231
Xenograft
Breast
CDKN2A, CDKN2B, BRAF, KRAS, TERT, TP53
4
MDA-MB-468
Xenograft
Breast
PTEN, RB1, TP53
N/A
MIAPaCa-2
Xenograft
Pancreatic
KRAS, TP53
8
MOLM-13
Xenograft
Blood
FLT3, KMT2A-MLLT3 fusion
14
NCI-H1703
Xenograft
Lung
CDKN2A, TP53
3
NCI-H1975
Xenograft
Lung
EGFR, PIK3CA, TP53
6
NCI-H460
Xenograft
Lung
KRAS, PIK3CA, STK11, TP53
5
NCI-N87
Xenograft
Gastric
ERBB3, TP53
6
OCI-AML-3
Xenograft
Blood
DNMT3A, NRAS, NPM1
2
OCI-Ly1
Xenograft
Blood
Unavailable
N/A
OVCAR8
Xenograft
Ovarian
CTNNB1, ERBB2, KRAS, TP53
8

*Other Models are possible, please contact us for details

WHY WORK WITH

RINCON BIO?

DOMESTIC QUALITY at COMPETITIVE PRICES

 

When you work with Rincon Bio, rest assured that all cancer efficacy studies will be performed in the USA, at competitive prices

SPEED TO INITIATION
 

Most efficacy studies can be initiated within two business days.

PERSONAL TOUCH

 

We love our clients!  We are easy to work with.  And we take a personal interest in our clients and their studies.  

VIVARIUMS

Our vivariums are equipped with mouse towers, biosafety cabinets, and an IVIS imaging system.

Email: info@rinconbio.com
Tel:  760-713-6613

Utah: 

3900 N Traverse Mountain Blvd

Suite 100

Lehi, UT 84043

California: 

3156 Vista Way, Suite 220

Oceanside, CA 92056

 

CONTACT US
bottom of page